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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP45
All Species:
13.64
Human Site:
T614
Identified Species:
23.08
UniProt:
Q70EL2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70EL2
NP_001073950
814
91733
T614
L
S
Q
S
Y
I
T
T
S
K
E
C
S
I
Q
Chimpanzee
Pan troglodytes
XP_001139771
814
91702
T614
L
S
Q
S
Y
I
T
T
S
K
E
C
S
I
Q
Rhesus Macaque
Macaca mulatta
XP_001085248
815
91829
T615
L
S
Q
T
Y
I
T
T
S
K
E
C
S
V
Q
Dog
Lupus familis
XP_539054
796
87704
L606
E
C
S
V
Q
S
C
L
Y
Q
F
T
S
M
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K387
813
90343
T613
L
S
Q
S
Y
V
T
T
S
K
E
C
S
V
Q
Rat
Rattus norvegicus
Q2KJ09
826
93743
A618
M
N
E
D
P
E
T
A
F
C
T
L
A
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506389
799
87920
C608
K
E
C
S
V
Q
S
C
L
Y
Q
F
T
S
V
Chicken
Gallus gallus
O57429
357
40913
V168
S
R
V
S
D
L
F
V
G
Q
L
K
S
S
L
Frog
Xenopus laevis
Q6PAW2
901
101274
A619
D
S
M
E
A
M
A
A
V
E
N
G
N
A
D
Zebra Danio
Brachydanio rerio
A8HAL1
815
90431
V625
L
A
S
R
T
A
P
V
K
Q
E
C
S
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121285
844
94413
I628
E
N
S
S
S
T
I
I
L
A
N
D
K
S
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790411
1122
123641
K642
S
E
E
G
K
V
V
K
E
S
M
N
T
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FPT5
1083
120752
V719
S
E
A
G
F
M
A
V
S
G
N
D
K
T
V
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
L283
H
T
V
F
E
G
S
L
E
S
S
I
V
C
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.4
72.2
N.A.
77.4
38.7
N.A.
63.7
20.1
38.5
38
N.A.
N.A.
29.3
N.A.
29.9
Protein Similarity:
100
99.7
96.6
81.5
N.A.
85.3
59.6
N.A.
75.5
29.7
56.4
56.6
N.A.
N.A.
49.1
N.A.
45.3
P-Site Identity:
100
100
86.6
6.6
N.A.
86.6
6.6
N.A.
6.6
13.3
6.6
26.6
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
100
26.6
N.A.
100
40
N.A.
26.6
26.6
26.6
53.3
N.A.
N.A.
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.6
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
8
8
15
15
0
8
0
0
8
8
0
% A
% Cys:
0
8
8
0
0
0
8
8
0
8
0
36
0
8
0
% C
% Asp:
8
0
0
8
8
0
0
0
0
0
0
15
0
0
8
% D
% Glu:
15
22
15
8
8
8
0
0
15
8
36
0
0
0
15
% E
% Phe:
0
0
0
8
8
0
8
0
8
0
8
8
0
0
0
% F
% Gly:
0
0
0
15
0
8
0
0
8
8
0
8
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
22
8
8
0
0
0
8
0
15
8
% I
% Lys:
8
0
0
0
8
0
0
8
8
29
0
8
15
8
0
% K
% Leu:
36
0
0
0
0
8
0
15
15
0
8
8
0
0
8
% L
% Met:
8
0
8
0
0
15
0
0
0
0
8
0
0
8
0
% M
% Asn:
0
15
0
0
0
0
0
0
0
0
22
8
8
8
0
% N
% Pro:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
29
0
8
8
0
0
0
22
8
0
0
0
29
% Q
% Arg:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
22
36
22
43
8
8
15
0
36
15
8
0
50
22
0
% S
% Thr:
0
8
0
8
8
8
36
29
0
0
8
8
15
8
8
% T
% Val:
0
0
15
8
8
15
8
22
8
0
0
0
8
22
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
29
0
0
0
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _